YearAwardCeremonyNominationMovie2013Gold Derby TV AwardGold Derby AwardsTV Movie/Mini Lead ActressThe Big C (2010)2013OFTA Television AwardOnline Film & Television AssociationBest Actress in a Motion Picture or MiniseriesThe Big C (2010)2013Satellite AwardSatellite AwardsBest Actress in a Miniseries or a Motion Picture Made for TelevisionThe Big C (2010)2012Golden GlobeGolden Globes, USABest Performance by an Actress in a Television Series - Comedy or MusicalThe Big C (2010)2012OFTA Television AwardOnline Film & Television AssociationBest Actress in a Comedy SeriesThe Big C (2010)2012Satellite AwardSatellite AwardsBest Actress in a Motion PictureHyde Park on Hudson (2012)2011Primetime EmmyPrimetime Emmy AwardsOutstanding Lead Actress in a Comedy SeriesThe Big C (2010)2011Dorian AwardGay and Lesbian Entertainment Critics Association (GALECA)TV Comedy Performance of the YearThe Big C (2010)2011Gold Derby TV AwardGold Derby AwardsComedy Lead ActressThe Big C (2010)2011OFTA Television AwardOnline Film & Television AssociationBest Actress in a Comedy SeriesThe Big C (2010)2011Satellite AwardSatellite AwardsBest Actress in a Series, Comedy or MusicalThe Big C (2010)2010Best ActressMethod FestFeature FilmThe City of Your Final Destination (2009)2009Gold Derby TV AwardGold Derby AwardsTV Movie/Mini Actress of the DecadeJohn Adams (2008)2008OscarAcademy Awards, USABest Performance by an Actress in a Leading RoleThe Savages (2007)2008HFCS AwardHouston Film Critics Society AwardsBest ActressThe Savages (2007)2008ALFS AwardLondon Critics Circle Film AwardsActress of the YearThe Savages (2007)2008OFTA Film AwardOnline Film & Television AssociationBest ActressThe Savages (2007)2008OFTA Television AwardOnline Film & Television AssociationBest Actress in a Motion Picture or MiniseriesJohn Adams (2008)2008OFCS AwardOnline Film Critics Society AwardsBest ActressThe Savages (2007)2008Satellite AwardSatellite AwardsBest Actress in a Miniseries or a Motion Picture Made for TelevisionJohn Adams (2008)2007EDA AwardAlliance of Women Film JournalistsBest ActressThe Savages (2007)2007EDA Female Focus AwardAlliance of Women Film JournalistsWomen's Image AwardThe Savages (2007)2007CFCA AwardChicago Film Critics Association AwardsBest ActressThe Savages (2007)2007DFWFCA AwardDallas-Fort Worth Film Critics Association AwardsBest ActressThe Savages (2007)2007DFCS AwardDetroit Film Critic Society, USBest ActressThe Savages (2007)2007Gotham Independent Film AwardGotham AwardsBest Ensemble PerformanceThe Savages (2007)2007Satellite AwardSatellite AwardsBest Actress in a Motion Picture, DramaThe Savages (2007)2007SLFCA AwardSt. Louis Film Critics Association, USBest ActressThe Savages (2007)2007VVFP AwardVillage Voice Film PollBest ActressThe Savages (2007)2006Golden GlobeGolden Globes, USABest Performance by an Actress in a Motion Picture - Comedy or MusicalThe Squid and the Whale (2005)2006Saturn AwardAcademy of Science Fiction, Fantasy & Horror Films, USABest ActressThe Exorcism of Emily Rose (2005)2006AFI AwardAustralian Film InstituteBest Lead ActressJindabyne (2006)2006Chainsaw AwardFangoria Chainsaw AwardsChick You Don't Wanna Mess With (Best Heroine)The Exorcism of Emily Rose (2005)2006FCCA AwardFilm Critics Circle of Australia AwardsBest Actress in a Lead RoleJindabyne (2006)2006Gold Derby AwardGold Derby AwardsEnsemble CastThe Squid and the Whale (2005)2006IF AwardIF AwardsBest ActressJindabyne (2006)2006Independent Spirit AwardIndependent Spirit AwardsBest Female LeadThe Squid and the Whale (2005)2006ALFS AwardLondon Critics Circle Film AwardsActress of the YearKinsey (2004)2006VFCC AwardVancouver Film Critics CircleBest ActressThe Squid and the Whale (2005)2005OscarAcademy Awards, USABest Performance by an Actress in a Supporting RoleKinsey (2004)2005Golden GlobeGolden Globes, USABest Performance by an Actress in a Supporting Role in a Motion PictureKinsey (2004)2005ACCAAwards Circuit Community AwardsBest Actress in a Leading RoleThe Squid and the Whale (2005)2005ACCAAwards Circuit Community AwardsBest Cast EnsembleThe Squid and the Whale (2005)2005Critics Choice AwardBroadcast Film Critics Association AwardsBest Supporting ActressKinsey (2004)2005DFWFCA AwardDallas-Fort Worth Film Critics Association AwardsBest Supporting ActressKinsey (2004)2005Gold Derby AwardGold Derby AwardsSupporting ActressKinsey (2004)2005OFTA Film AwardOnline Film & Television AssociationBest Supporting ActressKinsey (2004)2005OFCS AwardOnline Film Critics Society AwardsBest Supporting ActressKinsey (2004)2005Golden Satellite AwardSatellite AwardsBest Actress in a Motion Picture, DramaP.S. (2004)2005Golden Satellite AwardSatellite AwardsBest Actress in a Supporting Role, DramaKinsey (2004)2005ActorScreen Actors Guild AwardsOutstanding Performance by a Female Actor in a Supporting RoleKinsey (2004)2005SLFCA AwardSt. Louis Film Critics Association, USBest ActressThe Squid and the Whale (2005)2005VFCC AwardVancouver Film Critics CircleBest ActressKinsey (2004)2005VVFP AwardVillage Voice Film PollBest Supporting PerformanceThe Squid and the Whale (2005)2004BAFTA Film AwardBAFTA AwardsBest Performance by an Actress in a Supporting RoleMystic River (2003)2004COFCA AwardCentral Ohio Film Critics AssociationBest Supporting ActressMystic River (2003)2004Gold Derby AwardGold Derby AwardsEnsemble CastMystic River (2003)2004Gold Derby TV AwardGold Derby AwardsComedy Guest ActressFrasier (1993)2004OFTA Television AwardOnline Film & Television AssociationBest Guest Actress in a Comedy SeriesFrasier (1993)2004PFCS AwardPhoenix Film Critics Society AwardsBest Ensemble ActingLove Actually (2003)2004ActorScreen Actors Guild AwardsOutstanding Performance by a Cast in a Motion PictureMystic River (2003)2004WAFCA AwardWashington DC Area Film Critics Association AwardsBest Supporting ActressKinsey (2004)2003ACCAAwards Circuit Community AwardsBest Actress in a Supporting RoleMystic River (2003)2003DVD Premiere AwardDVD Exclusive AwardsBest ActressLush (1999)2002OFTA Television AwardOnline Film & Television AssociationBest Actress in a Motion Picture or MiniseriesWild Iris (2001)2002Golden Satellite AwardSatellite AwardsBest Performance by an Actress in a Miniseries or a Motion Picture Made for TelevisionWild Iris (2001)2001OscarAcademy Awards, USABest Actress in a Leading RoleYou Can Count on Me (2000)2001Golden GlobeGolden Globes, USABest Performance by an Actress in a Motion Picture - DramaYou Can Count on Me (2000)2001CFCA AwardChicago Film Critics Association AwardsBest ActressYou Can Count on Me (2000)2001Chlotrudis AwardChlotrudis AwardsBest ActressYou Can Count on Me (2000)2001Independent Spirit AwardIndependent Spirit AwardsBest Female LeadYou Can Count on Me (2000)2001OFTA Film AwardOnline Film & Television AssociationBest ActressYou Can Count on Me (2000)2001OFCS AwardOnline Film Critics Society AwardsBest ActressYou Can Count on Me (2000)2001PFCS AwardPhoenix Film Critics Society AwardsBest Actress in a Leading RoleYou Can Count on Me (2000)2001Golden Satellite AwardSatellite AwardsBest Performance by an Actress in a Motion Picture, DramaYou Can Count on Me (2000)2001ActorScreen Actors Guild AwardsOutstanding Performance by a Female Actor in a Leading RoleYou Can Count on Me (2000)2001TFCA AwardToronto Film Critics Association AwardsBest Supporting Performance, FemaleThe House of Mirth (2000)2000ACCAAwards Circuit Community AwardsBest Actress in a Leading RoleYou Can Count on Me (2000)1999Blockbuster Entertainment AwardBlockbuster Entertainment AwardsFavorite Supporting Actress - DramaThe Truman Show (1998)1998ACCAAwards Circuit Community AwardsBest Actress in a Supporting RoleThe Truman Show (1998)